At the same time, the poly(lactic-co-glycolic acid)-indocyanine green (PLGA-ICG) component (PI) implanted eukaryotic-prokaryotic vesicle (EPV) nanoplatform PI@EPV can significantly enhance CTL-induced tumor-specific immunity and show synergistic anti-tumor effects after combined laser irradiation (808 nm) and further enhances CD8 + CTLs infiltration in the combination treatment group compared with the unirradiated treatment thereby resulting in a stronger tumor inhibitory effect (183)
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